Through analysis of human clinical specimens and other data, we aim to discover new immune factors against infectious diseases and cancer, leading to the development of new vaccines and therapies.

In particular, we emphasize translational research based on individual immunological differences.

For example, it has been reported that elderly people with advanced immune senescence have "a higher risk of developing concomitant cancer and infectious diseases" and that "vaccines are not sufficiently effective.

By understanding the immunological backgrounds of individuals in different age groups and for different diseases, we will identify problems and issues in current diagnosis and treatment, establish a technological platform for personalized and stratified medicine, and develop new vaccines, immunotherapy, diagnostic biomarkers, etc. by utilizing this technological platform.

We believe that a more advanced analysis platform is needed to understand the characteristics of the complex human immune system and to identify problems.

Therefore, our laboratory has developed a world-class analysis platform (high-level immunological analysis platform) that enables multifaceted, high-resolution analysis of differences in the immune system and responses to immunogens in each individual.

By utilizing the above platform, we hope to extract the issues of current vaccines and therapies from the analysis of various human clinical specimens, and to validate novel therapies or diagnostic biomarkers to solve such issues at the in vivo level in non-clinical studies using rodents and non-human primates, and hopefully return them to clinical use. We would like to extract novel therapeutic or diagnostic biomarkers to solve such problems.

We aim to establish immunological analysis systems, search for biomarkers, and establish new preventive and therapeutic methods directly related to human clinical applications by comparing human clinical specimens, genetically modified mice as animal models, and non-human primate monkey specimens on a side-by-side basis. Our major research focuses on cancer-related research and research related to infectious diseases.